Three things plug into Cell2Jack. Your home phone goes in the Phone port. The power adapter goes in the 5V in port. Your cell phone charging cable can go in the 5V out port, which is optional and only charges your cell phone while it sits nearby.
Connect the home phone straight to Cell2Jack, not through a wall jack. The wall jack comes later, after calls work. Amazon describes setup as quick and hassle-free.
For the full walkthrough, open the setup page. To pair your cell phone, see pair your cell phone the first time.